Sigma-Aldrich/Thioctic acid/Y0000546/

• CAS Number 1077-28-7

• Empirical Formula (Hill Notation) C₈H₁₄O₂S₂

• Molecular Weight 206.33

•  Beilstein Registry Number 81853

•  MDL number MFCD00005474

•  PubChem Substance ID 329831010

Properties:

Description:

Caution

Please find SDS provided by EDQM here..

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

Unit quantity: 110 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Biochem/physiol Actions

Antioxidant and coenzyme needed for the activity of enzyme complexes such as those of pyruvate dehydrogenase and glycine decarboxylase. Exogenous thioctic acid is reduced intracellularly by two or more enzymes. The reduced form then influences a number of cell processes by direct radical scavenging, recycling of other antioxidants, increasing glutathione synthesis, and modulating transcription factor activity particularly that of NF-κB. Decreases the phagocytosis of myelin by macrophages.

Safety:

Symbol 

  GHS07