Properties:
RelatedCategories | BloodandUrineChemistryAssayKits,CellBIOLOGy,EnzymaticActivityAssayKits,EnzymaticKitsfortheQuantitationofNutrientsandMetabolites,MetabolismAssayKitsA-Z, |
storagetemp. | −20°C |
Description:
Generaldescription
ThecoagulationFactorIX(orChristmasfactor)(EC3.4.21.22)isavitaminK-dependentserineprotease.FactorIXisproducedasaninactiveprecursorandisactivatedviacleavagebyeitherfactorXIa(contactpathway)orfactorVIIa(tissuefactorpathway).Inthepresenceofcalciumionsandnegativelychargedmembranephospholipids,activatedfactorIX(FIXa)thenbindstotheactivatedFactorVIII(FVIIIa)andproteolyticallyactivatesfactorX(FX)tofactorXa(FXa).
SuitABIlity
SuitabletodeterminetheactivityofpurifiedFactorIXandtodetecttheactivityofFactorIXinplasmaandserum.