| Immunogen | Bovinebrainmicrotubuleprotein. |
| Clone | AP20 |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Mouse |
| Specificity | MAB3418bindsspecificallytoMAP-2. |
| Isotype | IgG |
| SpeciesReactivity | - Bovine
- Chicken
- Human
- Mouse
- Rat
- Xenopus
- Quail
|
| SpeciesReactivityNote | Ratandmouse.Expectedtocross-reactwithhuman,cow,chicken,quail,andXenopus. |
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Thisgeneencodesaproteinthatbelongstothemicrotubule-associatedproteinfamily.Theproteinsofthisfamilyarethoughttobeinvolvedinmicrotubuleassembly,whichisanessentialstepinneurogenesis.Theproductsofsimilargenesinratandmouseareneuron-specificcytoskeletalproteinsthatareenrichedindentrites,implicatingaroleindeterminingandstABIlizingdentriticshapeduringneurondevelopment.Anumberofalternativelysplicedvariantsencodingdistinctisformshavebeendescribed. |
| GeneSymbol | - MAP2
- MAP2B
- MAP-2
- MAP2C
- DKFZp686I2148
- MAP2A
|
| PurificationMethod | ProteinAPurfied |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P11137#TheexactfunctionofMAP2isunknownbutMAPsmaystabilizethemicrotubulesagainstdepolymerization.Theyalsoseemtohaveastiffeningeffectonmicrotubules. SIZE:1827aminoacids;199539Da PTM:MAP2A/cisphosphorylated.PhosphorylateduponDNAdamage,probablybyATMorATR. SIMILARITY:SwissProt:P11137##Contains3Tau/MAPrepeats. |
| MolecularWeight | 230kDa |