| Immunogen | Purifiedvimentinfrompigeyelens | 
| Clone | V9 | 
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. | 
| Host | Mouse | 
| Specificity | Recognizesa57-60kDaprotein.ShowsnocrossreactivitywithothercloselyrelatedintermediatefilamentproteinsincludingdesminandGFAP.Intissuesections,thisreagentshowspositivereactiononconnectivetissue,endothelialcells,vascularsmoothmusclecellsandastrocytes.Intissueculture,typicalintermediatefilamentprofilesareseeninfibroblastsandothercelltypes,whichcontainvimentin | 
| Isotype | IgG1 | 
| SpeciesReactivity | - Bovine
 - Canine
 - Chicken
 - Feline
 - Human
 - Monkey
 - Pig
 - Rat
 
  | 
| AntibodyType | MonoclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | AlongwiththeMICROFILaments(actins)andmicrotubules(tubulins),theintermediatefilamentsrepresentathirdclassofwell-characterizedcytoskeletalelements.Thesubunitsdisplayatissue-specificpatternofexpression.Desmin(MIM125660)isthesubunitspecificformuscleandvimentinthesubunitspecificformesenchymaltissue.[suppliedbyOMIM] | 
| GeneSymbol |  | 
| Non-ReactiveSpecies |  | 
| PurificationMethod | ProteinAPurfied | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P08670#Vimentinsareclass-IIIintermediatefilamentsfoundinvariousnon-epithelialcells,especiallymesenchymalcells. SIZE:466aminoacids;53652Da SUBUNIT:Homopolymer.ComponentofacomplexcomposedatleastofACTB,AP2M1,AP2A1,AP2A2,MEGF10andVIM.InteractswithHCVcoreprotein. TISSUESPECIFICITY:Highlyexpressedinfibroblasts,someexpressioninT-andB-lymphocytes,andlittleornoexpressioninBurkitt"slymphomacelllines.Expressedinmanyhormone-independentmammarycarcinomacelllines. PTM:Oneofthemostprominentphosphoproteinsinvariouscellsofmesenchymalorigin.Phosphorylationisenhancedduringcelldivision,atwhichtimevimentinfilamentsaresignificantlyreorganized. SIMILARITY:SwissProt:P08670##Belongstotheintermediatefilamentfamily.... | 
| MolecularWeight | 57-60kDa |