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| Note: The product is for research use only, not for use in diagnostic or therapeutic procedures |
|
| Product Name | Aggrecan (Cleaved-Asp369) Antibody |
| Synonyms | aggrecan core protein; cartilage-specific proteoglycan core protein; chondroitin sulfate proteoglycan core protein 1; CSPCP; CSPG1, PGCA; PGCA |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Aggrecan. |
| Immunogen Range | 320-369 |
| Clonality | Polyclonal |
| Application Dilutions | WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000 |
| Specificity | Aggrecan (Cleaved-Asp369) Antibody detects endogenous levels of fragment of activated Aggrecan resulting from cleavage adjacent to Asp369. |
| Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
| Physical Form | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage/Stability | Stable at -20°C for at least 1 year. |
| NCBI Gene Symbol | ACAN |
| Database Links |
Gene ID: 176 Swiss-Prot #: P16112 OMIM #: 155760 Unigene #: Hs.2159/Hs.616395 |
| Target Modification | Cleaved |
| Modification Sites | |
| Application Images | |
| Image 1 |
 Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Aggrecan (Cleaved-Asp369) Antibody. The picture on the right is blocked with the synthesized peptide. |
| Image 2 |
 Western blot analysis of lysates from Jurkat cells, treated with Etoposide 25uM 60', using Aggrecan (Cleaved-Asp369) Antibody. The lane on the right is blocked with the synthesized peptide. |
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