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Abnova/ACO1 (Human) IP-WB Antibody Pair/1kit/H00000048-PW2

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貨號: H00000048-PW2

品牌: Abnova

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- - Specification
  - Gene Info
  - Pathway
  - Related Products
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  Specification
  Product Description:
  This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  Reactivity:
  Human
  Quality Control Testing:
  Immunoprecipitation-Western Blot (IP-WB)Immunoprecipitation of ACO1 transfected lysate using rabbit polyclonal anti-ACO1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-ACO1.
  Supplied Product:
  Antibody pair set content:1. Antibody pair for IP: rabbit polyclonal anti-ACO1 (300 ul)2. Antibody pair for WB: mouse purified polyclonal anti-ACO1 (50 ug)
  Storage Instruction:
  Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  MSDS:
  Download
  Datasheet:
  Download
  Applications
  Immunoprecipitation-Western Blot
  Protocol Download
  Application Image
  Immunoprecipitation-Western Blot
  Gene Information
  Entrez GeneID:
  48
  Gene Name:
  ACO1
  Gene Alias:
  ACONS,IREB1,IREBP,IREBP1,IRP1
  Gene Description:
  aconitase 1, soluble
  Omim ID:
  100880
  Gene Ontology:
  Hyperlink
  Gene Summary:
  Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs).IREs are stem-loop structures found in the 5" UTR of ferritin mRNA, and in the 3" UTR of transferrin receptor mRNA.The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA.Thus, IREB1 plays a central role in cellular iron homeostasis.It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes. [provided by RefSeq
  Other Designations:
  OTTHUMP00000021176,OTTHUMP00000021177,OTTHUMP00000045233,aconitase 1,aconitate hydratase,citrate hydro-lyase,ferritin repressor protein,iron regulatory protein 1,iron-responsive element binding protein 1
  Gene Pathway
  Biosynthesis of alkaloids derived from histidine and purine
  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
  Biosynthesis of alkaloids derived from shikimate pathway
  Biosynthesis of alkaloids derived from terpenoid and polyketide
  Biosynthesis of phenylpropanoids
  Biosynthesis of plant hormones
  Biosynthesis of terpenoids and steroids
  Citrate cycle (TCA cycle)
  Glyoxylate and dicarboxylate metabolism
  Metabolic pathways
  Reductive carboxylate cycle (CO2 fixation)
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Abnova/ACO1 (Human) IP-WB Antibody Pair/1kit/H00000048-PW2

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