| Immunogen | PMA-treatedU937cells |
| Epitope | domains3-6ofhumanPECAM-1 |
| Clone | HC1/6 |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Mouse |
| Specificity | Reactswitha130-140kDatransmembranousglycoproteinthatisexpressedwidelyamongstcellsofthevascularcompartment.CD31isexpressedonplatelets,culturedendothelialcells,monocytes,normaltissuemacrophagesintonsil,lungandkidneyaswellasinskinbiopsiesfromconditionssuchassarcoidosisandlepromatousleprosy. FUSIONPARTNER:P3-x63Ag8.653myelomacellline |
| Isotype | IgG1 |
| SpeciesReactivity | |
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| GeneSymbol | - PECAM1
- EndoCAM
- GPIIA
- PECAM-1
- CD31
- CD31/EndoCAM
|
| PurificationMethod | ProteinAPurfied |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P16284#Thisproteinisacelladhesionmoleculeexpressedonplateletsandatendothelialcellintercellularjunctions. SIZE:738aminoacids;82536Da SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein. TISSUESPECIFICITY:Longisoformpredominatesalltissuesexamined,isoformDelta12wasdetectedonlyintracheaandisoformDelta14-15onlyinlung,isoformDelta14wasdetectedinalltissuesexaminedwiththestrongestexpressioninheart. PTM:PhosphorylatedonSerandTyrresiduesaftercellularactivation. SIMILARITY:SwissProt:P16284##Contains6Ig-likeC2-type(immunoglobulin-like)domains. |