| Immunogen | KLH-conjugatedlinearpeptidecorrespondingtotheC-terminusofhumanS100A4. |
| Epitope | C-terminus |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | ThisantibodyrecognizesS100A4attheC-terminus. |
| SpeciesReactivity | - Human
- Mouse
- Rat
- Bovine
- Canine
- Horse
|
| SpeciesReactivityNote | DemonstratedtoreactwithHuman,Mouse,andRat. PredictedtoreactwithBovine,Canine,andEquinebasedon100%sequencehomology. |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | TheproteinencodedbythisgeneisamemberoftheS100familyofproteinscontaining2EF-handcalcium-bindingmotifs.S100proteinsarelocalizedinthecytoplasmand/ornucleusofawiderangeofcells,andinvolvedintheregulationofanumberofcellularprocessessuchascellcycleprogressionanddifferentiation.S100genesincludeatleast13memberswhicharelocatedasaclusteronchromosome1q21.Thisproteinmayfunctioninmotility,invasion,andtubulinpolymerization.Chromosomalrearrangementsandalteredexpressionofthisgenehavebeenimplicatedintumormetastasis.Multiplealternativelysplicedvariants,encodingthesameprotein,havebeenidentified.[providedbyRefSeq,Jul2008]. |
| GeneSymbol | |
| PurificationMethod | AffinityPurfied |
| UniProtNumber | |
| UniProtSummary | SUBUNITSTRUCTURE:Homodimer.InteractswithPPFIBP1inacalcium-dependentmode.
TISSUESPECIFICITY:Ubiquitouslyexpressed.
SEQUENCESIMILARITIES:BelongstotheS-100family.
Contains2EF-handdomains. |
| MolecularWeight | ~12kDaobserved |