| Immunogen | PurifiedbovineGFAP |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | RecognizesGlialFibrillaryAcidicProtein(GFAP). |
| SpeciesReactivity | |
| SpeciesReactivityNote | Human,rat,bovineandcanine.ItisexpectedthattheantibodywillreactwithmostmammalianGFAPduetohomology.Reactivitywithotherspecieshasnotbeenconfirmed. |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Thisgeneencodesoneofthemajorintermediatefilamentproteinsofmatureastrocytes.Itisusedasamarkertodistinguishastrocytesfromotherglialcellsduringdevelopment.MutationsinthisgenecauseAlexanderdisease,araredisorderofastrocytesinthecentralnervoussystem.Anadditionaltranscriptvarianthasbeendescribed,butitsfulllengthsequencehasnotbeendetermined. |
| GeneSymbol | |
| PurificationMethod | Unpurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:Q28115#GFAP,aclass-IIIintermediatefilament,isacell-specificmarkerthat,duringthedevelopmentofthecentralnervoussystem,distinguishesastrocytesfromotherglialcells. SIZE:428aminoacids;49512Da SUBCELLULARLOCATION:Cytoplasm.Note=Associatedwithintermediatefilaments. SIMILARITY:SwissProt:Q28115##Belongstotheintermediatefilamentfamily. |
| MolecularWeight | 50kDa |