| Immunogen | Syntheticphosphopeptidefromhumanmyosin,smoothandnon-muscleregulatorylightchain. |
| Epitope | phospho-specific(Ser19) |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | Myosin,human,smoothandnon-muscleregulatorylightchain,phosphoSer19.ByWesternblottheantibodyrecognizesthe~20kDaphosphorylatedprotein.Theimmunogensequencediffersfromthatofthesarcomeric/cardiacformofmyosinregulatorylightchain.Theantibodyrecognizesmonophosphorylated(pSer19)anddiphosporylated(pThr18-pSer19)formsoftheprotein.Reactivitytonon-phosphorylatedhumanmyosin,smoothandnon-muscleregulartorylightchainisminimal(lessthan1%)byELISA. |
| SpeciesReactivity | |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | MyosinisahexamericATPasecellularmotorprotein.Itiscomposedoftwoheavychains,twononphosphorylatablealkalilightchains,andtwophosphorylatableregulatorylightchains.Thisgeneencodesamyosinalkalilightchainexpressedinbothslow-twitchskeletalmuscleandinnonmuscletissue. |
| GeneSymbol | |
| Modifications | |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P14649#Regulatorylightchainofmyosin.Doesnotbindcalcium. SIZE:208aminoacids;22764Da SUBUNIT:Myosinisanhexamerof2heavychainsand4lightchains. SIMILARITY:SwissProt:P14649##Contains3EF-handdomains. |