| Immunogen | SyntheticLinearPeptide |
| Epitope | C-Terminus |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | RecognizesAquaporin4. |
| SpeciesReactivity | |
| SpeciesReactivityNote | Theantibodyhasnotyetbeentestedforcross-reactivitytootherspecies.
Theimmunogenshows94%similaritytomouse,88%tobovine,86%torabbitand82%tohumanAQP4(hAQP4). |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Thisgeneencodesamemberoftheaquaporinfamilyofintrinsicmembraneproteinsthatfunctionaswater-selectivechannelsintheplasmamembranesofmanycells.Theencodedproteinisthepredominantaquaporinfoundinbrain.Twoalternativelysplicedtranscriptvariantsencodingdistinctisoformshavebeenfoundforthisgene. |
| GeneSymbol | - AQP4
- MIWC
- WCH4
- AQP-4
- aquaporin-4
- HMIWC2
- Aquaporin-4
- MGC22454
|
| PurificationMethod | ImmunoAffinityPurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P55087#Formsawater-specificchannel.Osmoreceptorwhichregulatesbodywaterbalanceandmediateswaterflowwithinthecentralnervoussystem. SIZE:323aminoacids;34830Da SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein. TISSUESPECIFICITY:Brain-muscle>heart,kidney,lung,andtrachea. DOMAIN:SwissProt:P55087Aquaporinscontaintwotandemrepeatseachcontainingthreemembrane-spanningdomainsandapore-formingloopwiththesignaturemotifAsn-Pro-Ala(NPA). SIMILARITY:BelongstotheMIP/aquaporin(TC1.A.8)family. |
| MolecularWeight | ~34kDa |