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| Note: The product is for research use only, not for use in diagnostic or therapeutic procedures |
|
| Product Name | PKR (Phospho-Thr451) Antibody |
| Synonyms | Interferon-inducible RNA-dependent protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Protein kinase RNA-activated; PKR; p68 kinase; P1/eIF-2A protein kinase |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PKR around the phosphorylation site of Thr451. |
| Immunogen Range | 418-467 |
| Clonality | Polyclonal |
| Application Dilutions | IHC: 1:50~1:100 ELISA: 1:20000 |
| Specificity | PKR (Phospho-Thr451) Antibody detects endogenous levels of PKR only when phosphorylated at Thr451. |
| Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
| Physical Form | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage/Stability | Stable at -20°C for at least 1 year. |
| NCBI Gene Symbol | EIF2AK2 |
| Database Links |
Gene ID: 5610 Swiss-Prot #: P19525 OMIM #: 176871 Unigene #: Hs.131431 |
| Target Modification | Phospho |
| Modification Sites | H:T451 |
| Application Images | |
| Image 1 |
 Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using PKR (Phospho-Thr451) Antibody. The picture on the right is blocked with the phospho peptide. |
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