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| Note: The product is for research use only, not for use in diagnostic or therapeutic procedures |
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| Product Name | MDM2 (Phospho-Ser186+Ser188) Antibody |
| Synonyms | Double minute 2 protein; HDM2; Oncoprotein Mdm2; p53-binding protein Mdm2; Ubiquitin-protein ligase E3 Mdm2 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MDM2 around the phosphorylation site of Ser186 and Ser188. |
| Immunogen Range | 151-200 |
| Clonality | Polyclonal |
| Application Dilutions | IF: 1:100~1:500 ELISA: 1:20000 |
| Specificity | MDM2 (Phospho-Ser186+Ser188) Antibody detects endogenous levels of MDM2 only when phosphorylated at Ser186 and Ser188. |
| Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
| Physical Form | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage/Stability | Stable at -20°C for at least 1 year. |
| NCBI Gene Symbol | MDM2 |
| Database Links |
Gene ID: 4193 Swiss-Prot #: Q00987 OMIM #: 164785 Unigene #: Hs.567303 |
| Target Modification | Phospho |
| Modification Sites | H:S186+S188 |
| Application Images | |
| Image 1 |
 Immunofluorescence analysis of HeLa cells, using MDM2 (Phospho-Ser186+Ser188) Antibody. The picture on the right is blocked with the phospho peptide. |
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