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| Note: The product is for research use only, not for use in diagnostic or therapeutic procedures |
|
| Product Name | CD18/ITGB2 (Phospho-Thr758) Antibody |
| Synonyms | CD18; cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 beta; complement receptor C3 beta; integrin beta-2; ITB2 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CD18/ITGB2 around the phosphorylation site of Thr758. |
| Immunogen Range | 720-769 |
| Clonality | Polyclonal |
| Application Dilutions | WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:40000 |
| Specificity | CD18/ITGB2 (Phospho-Thr758) Antibody detects endogenous levels of CD18/ITGB2 only when phosphorylated at Thr758. |
| Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
| Physical Form | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage/Stability | Stable at -20°C for at least 1 year. |
| NCBI Gene Symbol | ITGB2 |
| Database Links |
Gene ID: 3689 Swiss-Prot #: P05107 OMIM #: 116920/600065 Unigene #: Hs.375957 |
| Target Modification | Phospho |
| Modification Sites | H:T758 M:T760 R:T757 |
| Application Images | |
| Image 1 |
 Immunofluorescence analysis of HepG2 cells, using CD18/ITGB2 (Phospho-Thr758) Antibody. The picture on the right is blocked with the phospho peptide. |
| Image 2 |
 Western blot analysis of lysates from COS7 cells treated with EGF 200ng/ml 30', using CD18/ITGB2 (Phospho-Thr758) Antibody. The lane on the right is blocked with the phospho peptide. |
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