The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
LAT (Phospho-Tyr191) Antibody
Synonyms
36 kDa phospho-tyrosine adaptor protein; Linker for activation of T cells; p36-38; pp36
Immunogen
The antiserum was produced against synthesized peptide derived from human LAT around the phosphorylation site of Tyr191.
Immunogen Range
191-240
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000
Specificity
LAT (Phospho-Tyr191) Antibody detects endogenous levels of LAT only when phosphorylated at Tyr191.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
LAT
Database Links
Gene ID: 27040 Swiss-Prot #: O43561
OMIM #: 602354 Unigene #: Hs.632179
Target Modification
Phospho
Modification Sites
H:Y191 M:Y195 R:Y195
Application Images
Image 1
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using LAT (Phospho-Tyr191) Antibody. The picture on the right is blocked with the phospho peptide.
Image 2
Western blot analysis of lysates from NIH/3T3 cells, using LAT (Phospho-Tyr191) Antibody. The lane on the right is blocked with the phospho peptide.