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| Note: The product is for research use only, not for use in diagnostic or therapeutic procedures |
|
| Product Name | CBL (Phospho-Tyr700) Antibody |
| Synonyms | Cas-Br-M (murine) ecotropic retroviral transforming; CBL E3 ubiquitin protein ligase; CBL2; Proto-oncogene c-CBL; Signal transduction protein CBL |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CBL around the phosphorylation site of Tyr700. |
| Immunogen Range | 666-715 |
| Clonality | Polyclonal |
| Application Dilutions | WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000 |
| Specificity | CBL (Phospho-Tyr700) Antibody detects endogenous levels of CBL only when phosphorylated at Tyr700. |
| Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
| Physical Form | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage/Stability | Stable at -20°C for at least 1 year. |
| NCBI Gene Symbol | CBL |
| Database Links |
Gene ID: 867 Swiss-Prot #: P22681 OMIM #: 165360 Unigene #: Hs.504096 |
| Target Modification | Phospho |
| Modification Sites | H:Y700 M:Y698 R:Y806 |
| Application Images | |
| Image 1 |
 Immunofluorescence analysis of HepG2 cells, using CBL (Phospho-Tyr700) Antibody. The picture on the right is blocked with the phospho peptide. |
| Image 2 |
 Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using CBL (Phospho-Tyr700) Antibody. The picture on the right is blocked with the phospho peptide. |
| Image 3 |
 Western blot analysis of lysates from K562 cells treated with Na3VO4 0.3nM, using CBL (Phospho-Tyr700) Antibody. The lane on the right is blocked with the phospho peptide. |
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