Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
ProductName | TyrosineHydroxylase(Phospho-Ser40)Antibody |
Synonyms | THisoform3;THisoforma;TH-4;TY3H;TYH;Tyrosine3-hydroxylase;Tyrosine3-monooxygenase;tyrosinehydroxylase |
Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanTyrosineHydroxylasearoundthephosphorylationsiteofSer40. |
ImmunogenRange | 41-90 |
Clonality | Polyclonal |
ApplicationDilutions | WB:1:500~1:1000IHC:1:50~1:100ELISA:1:40000 |
Specificity | TyrHydroxylase(Phospho-Ser40)AntibodydetectsendogenouslevelsofTyrHydroxylaseonlywhenphosphorylatedatSer40. |
Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
Storage/StABIlity | Stableat-20°Cforatleast1year. |
NCBIGeneSymbol | TH |
DatabaseLinks | GeneID: 7054 Swiss-Prot#: P07101 OMIM#: 191290/605407 Unigene#: Hs.435609/Hs.523414 |
TargetModification | Phospho |
ModificationSites | H:S71M:S40R:S40 |
ApplicationImages |
Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanbrain,usingTyrosineHydroxylase(Phospho-Ser40)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |
Image2 | WesternblotanalysisoflysatesfromRAW264.7cellstreatedwithUV30",usingTyrosineHydroxylase(Phospho-Ser40)Antibody.Thelaneontherightisblockedwiththephosphopeptide. |