| AlternateNames | - S100calciumbindingproteinA4
 - S100calcium-bindingproteinA4
 - fibroblast-specificprotein-1
 - leukemiamultidrugresistanceassociatedprotein
 - S100calciumbindingproteinA4(calciumprotein,calvasculin,metastasin,murineplacentalhomolog)
 - malignanttransformationsuppression1
 - S100calcium-bindingproteinA4(calciumprotein,calvasculin,metastasin,murineplacentalhomolog)
 - Metastasin
 - ProteinMts1
 - Placentalcalcium-bindingprotein
 - Calvasculin
 
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| BackgroundInformation | Fibroblast-specificprotein-1(FSP1)/S100A4isacytoplasmiccalcium-bindingproteinbelongingtotheS100superfamilyofwhichatleast21membershavebeenidentifiedsofar.ResearchersbelievethatFSP1/S1004Aishighlyexpressedinfibroblasts(Iwanoetal.,2001;Strutzetal.,1995),inepithelialandendothelialcellsundergoingepithelial-mesenchymaltransition(EMT)(Iwanoetal.,2002;ZeisbergandNeilson,2009),andepithelialcancercellsthatcompleteatransitiontoametastaticphenotype(Xueetal.,2003). |